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Thiamine Deficiency, Insulin Resistance and Diabetes

Thiamine Deficiency, Insulin Resistance and Diabetes

by | Jun 22, 2020 | Evidence Based, Inflammation, Science-Based, Wellness

The relationship between thiamine and diabetes mellitus (DM) has been reported in the literature (Luong & Nguyen, 2012). Thiamine acts as a coenzyme for transketolase (Tk) and for the pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase complexes. These enzymes play a fundamental role for intracellular glucose metabolism by increasing Krebs cycle activity (Luong & Nguyen, 2012).  [...]